Home2025 MLS Playoffs Conference Semifinals Preview: Who Will Reach the Final Four?

2025 MLS Playoffs Conference Semifinals Preview: Who Will Reach the Final Four?

MLS Conference Semifinals: Resuming the Showdown

With the November international break concluded, the Major League Soccer (MLS) playoffs are back in full swing. After a 13-day pause, teams like FC Cincinnati, Inter Miami CF, Philadelphia Union, San Diego FC, and others find themselves gearing up for high-stakes matches that are sure to entertain and excite. The anticipation for the semifinals intensifies, especially as almost all participating teams had to wait longer than a fortnight to jump back into competitive action.

Journey to the Semifinals

Each team now in the semis has weathered its own unique path. FC Cincinnati and Inter MiamiCF, along with Philadelphia Union, San Diego FC, and Vancouver Whitecaps, have faced different challenges and triumphant moments. Of particular note are Minnesota United FC and New York City FC, who have not played for 16 days and 20 days, respectively. It’s crucial to assess how this extended break may affect their performances as they resume competition.

Eastern Conference Matchups

FC Cincinnati vs. Inter Miami CF

Scheduled Match: Sunday, 5 p.m. ET

Star Attraction: Lionel Messi remains the focal point in every match featuring Inter Miami. After clinching the Golden Boot, Messi proved instrumental in Miami’s historic playoff advancement, netting five goals and an assist against Nashville SC in the previous round. His exceptional skills make him a player Cincinnati must strategize around, especially in knockout rounds where every moment counts.

Despite the challenge presented by Messi, Cincinnati boasts a lethal attacking trio in Evander, Brenner, and Kévin Denkey. Each player has had standout moments this season, with Evander tallying 18 goals and 15 assists, while Denkey and Brenner each offer potent offensive threats. Cincinnati’s earlier victories over Miami, including a 3-0 win in July, suggest they have what it takes to counteract Messi’s influence.

Tactical Wrinkle: Cincinnati’s head coach, Pat Noonan, has effectively manipulated defensive structures to create scoring opportunities. His tactical ingenuity and ability to adapt mid-match could be pivotal against Miami, who are yet to defeat Cincinnati this season.

Predictions: The match promises to be a nail-biter. Most analysts are leaning toward Inter Miami, citing Messi’s need for a final push toward the MLS Cup. However, Cincinnati’s formidable offense could surprise if they find openings in Miami’s defense.

Philadelphia Union vs. New York City FC

Scheduled Match: Sunday, 7:45 p.m. ET

Star Attraction: Philadelphia Union’s defense, led by Jakob Glesnes and Kai Wagner, stands out. With only 35 goals allowed during the regular season, this formidable backline, combined with Wagner’s ability to contribute offensively, positions them as a critical asset in their pursuit of the MLS Cup.

On the other hand, New York City FC faces setbacks, including a major injury to forward Alonso Martínez, which could severely hinder their attacking capabilities. As NYCFC plots a strategy, their depth will be tested without their top scorer.

Tactical Wrinkle: NYCFC will need to rethink their strategy without Martínez. Their attacking midfielders like Nicolás Fernández and Maxi Morález must step up to fill the void left by his absence. Philadelphia’s defense will look to capitalize on this lack of dynamism.

Predictions: Most analysts project the Union to come out ahead, especially given the defensive lapses in NYCFC’s lineup due to injuries.

Western Conference Matchups

Vancouver Whitecaps vs. LAFC

Scheduled Match: Saturday, 9:30 p.m. ET

Star Attraction: The attention is centered around Son Heung-Min and Denis Bouanga, LAFC’s dynamic attacking duo. Since his arrival, Son has impressed with his ability to deliver goals and assists, quickly proving himself a game-changer. The Whitecaps will be hard-pressed to limit their offensive contributions.

In contrast, Vancouver’s strength lies in solid defensive play and their ability to manage games from the back. They hope Tristan Blackmon can significantly disrupt LAFC’s attacking momentum, particularly as he returns from an injury that sidelined him.

Tactical Wrinkle: The versatility of LAFC to shift between a 4-3-3 and a 5-3-2 formation provides Manager Steve Cherundolo with a strategic advantage to exploit Vancouver’s weaknesses.

Predictions: The matchup is seen as tightly contested, with analysts divided over who will advance. While Vancouver’s defensive prowess could earn them an upset, the star power of LAFC appears to edge them ahead.

San Diego FC vs. Minnesota United FC

Scheduled Match: Monday, 10 p.m. ET

Star Attraction: Dayne St. Clair of Minnesota United has emerged as a savior this postseason, showcasing his shot-stopping abilities and winning critical penalty shootouts. With his impressive save percentage, he is a key player to watch.

San Diego’s attacking threats remain a focal point, particularly with players like Hirving Lozano and Anders Dreyer expected to impact the match. However, their fitness conditions raise questions about their availability to perform.

Tactical Wrinkle: San Diego’s young defensive line must focus on maintaining composure under Minnesota’s pressing tactics. A clean and precise execution can not only prevent mistakes but could give them a substantial edge.

Predictions: San Diego seems poised to pull off a win, given their recent successes and the energy of their roster. However, Minnesota’s established defensive prowess might pose significant challenges.


As the playoffs resume, these matchups promise to offer thrilling displays of athleticism, skill, and strategy. Each team brings its unique narratives and challenges, setting the stage for what could be an unforgettable round of MLS action.

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